Related Experiment Video
Updated: Jun 12, 2026
06:38
A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
[Kidney involvement in hematologic malignancies. Diagnostic approach]
N Jourde-Chiche1, B Dussol, L Daniel
1Centre de néphrologie et de transplantation rénale, hôpital de la Conception, 13385 Marseille cedex 05, France.
La Revue De Medecine Interne
|May 21, 2010
Summary
Kidney involvement is common in blood cancers (hematologic malignancies), impacting diagnosis and treatment. This review outlines diagnostic strategies for detecting and monitoring renal complications in various hematologic cancers.
Area of Science:
- Nephrology
- Hematology
- Oncology
Context:
- Kidney involvement is a frequent complication in hematologic malignancies.
- Renal complications are associated with adverse outcomes and treatment challenges.
- Hematologic cancers can affect all renal compartments: tubules, interstitium, glomeruli, and vessels.
Purpose:
- To review diagnostic tests for detecting and monitoring kidney involvement in hematologic malignancies.
- To clarify indications for renal biopsy in these patients.
- To propose diagnostic strategies for specific hematologic conditions including myeloma, Waldenström's disease, lymphomas, and leukemias.
Summary:
- Kidney damage in hematologic malignancies can manifest as acute renal failure, chronic kidney disease, or proteinuria.
- Diagnostic approaches depend on clinical presentation and include laboratory tests and imaging.
- This review focuses on diagnostic strategies, excluding treatment side effects.
Impact:
- Provides a framework for timely diagnosis and management of renal complications in hematologic malignancies.
- Aids clinicians in selecting appropriate diagnostic tests and understanding renal biopsy indications.
- Facilitates improved patient outcomes by addressing a critical aspect of hematologic cancer care.
Related Concept Videos
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
01:28Chronic Kidney Disease III: Interprofessional Care
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
01:19Imaging Studies VII: Vascular Imaging
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
01:16Kidney Transplant III: Nursing Management
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...