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Related Experiment Video

Updated: Jun 12, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

[Kidney involvement in hematologic malignancies. Diagnostic approach].

N Jourde-Chiche¹, B Dussol, L Daniel

¹Centre de néphrologie et de transplantation rénale, hôpital de la Conception, 13385 Marseille cedex 05, France.

La Revue De Medecine Interne

|May 21, 2010

Summary

Kidney involvement is common in blood cancers (hematologic malignancies), impacting diagnosis and treatment. This review outlines diagnostic strategies for detecting and monitoring renal complications in various hematologic cancers.

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Area of Science:

Nephrology
Hematology
Oncology

Context:

Kidney involvement is a frequent complication in hematologic malignancies.
Renal complications are associated with adverse outcomes and treatment challenges.
Hematologic cancers can affect all renal compartments: tubules, interstitium, glomeruli, and vessels.

Purpose:

To review diagnostic tests for detecting and monitoring kidney involvement in hematologic malignancies.
To clarify indications for renal biopsy in these patients.
To propose diagnostic strategies for specific hematologic conditions including myeloma, Waldenström's disease, lymphomas, and leukemias.

Summary:

Kidney damage in hematologic malignancies can manifest as acute renal failure, chronic kidney disease, or proteinuria.
Diagnostic approaches depend on clinical presentation and include laboratory tests and imaging.
This review focuses on diagnostic strategies, excluding treatment side effects.

Impact:

Provides a framework for timely diagnosis and management of renal complications in hematologic malignancies.
Aids clinicians in selecting appropriate diagnostic tests and understanding renal biopsy indications.
Facilitates improved patient outcomes by addressing a critical aspect of hematologic cancer care.