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Updated: Jun 12, 2026

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
Published on: September 26, 2022
Contact sensitization in patients with lower extremity dermatitis in the South Moravian region, Czech Republic
1Ist Department of Dermatovenereology, St Anna Faculty Hospital, Pekarská 53, Brno 656 91, Czech Republic. miroslav.necas@fnusa.cz
Objectives:
The aim of the study was to determine the frequency of contact sensitization in patients with lower extremity dermatitis.
Methods:
Between the years 2001 and 2007, the authors investigated 462 patients (mean age 49.1 years, 196 men and 266 women) with the eczema/dermatitis localized on their lower extremities, including feet. The patients were investigated with epicutaneous tests of the European Standard Series and also with other special patch tests.
Results:
The most frequent allergens were balsam of Peru, 44/462 (9.5%); wool alcohols, 41/462 (8.9%); nickel sulphate, 39/462 (8.4%); propolis, 35/462 (7.6%); fragrance mix, 34 (7.4%) and colophony, 29/462 (6.3%).
Conclusions:
In patients with lower extremity dermatitis the frequency of contact sensitization is still high, and therefore investigation with epicutaneous tests should belong to the routine dermatological diagnostic procedure in these patients.
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