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[Immunization with an anti-Lewis a antibody]
M H Gonçalves1, M C Sargento, M R Lopes
1Serviço de Imuno-Hemoterapia, Hospitais da Universidade de Coimbra.
Acta Medica Portuguesa
|January 1, 1991
Summary
This case study details immunological sensitization to a rare anti-Lewis a antibody. Further immuno-hematologic studies identified the specific antibody in the patient's serum.
Area of Science:
- Immunology
- Hematology
- Serology
Background:
- Immunological sensitization can lead to the development of irregular antibodies.
- The Lewis a antigen system is important in blood transfusion compatibility.
Observation:
- A case of immunological sensitization to a natural and irregular anti-Lewis a antibody was observed.
- Immuno-hematologic studies were performed on the patient's blood and saliva.
Findings:
- The specific seric antibody was identified using a panel of phenotype red cells.
- Analysis confirmed the presence of anti-Lewis a antibody.
Implications:
- Understanding irregular antibodies is crucial for preventing transfusion reactions.
- This case contributes to the knowledge of Lewis blood group system antibodies.