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Updated: Jun 12, 2026

Ex Vivo Culture of Circulating Tumor Cells in the Cerebral Spinal Fluid from Melanoma Patients to Study Melanoma-Associated Leptomeningeal Disease
Published on: March 29, 2024
Transient and spontaneously-remitting complex hallucinations in a patient with melanoma and brain metastases
1tish.lee@duke.edu
Background:
Neuropsychiatric sequelae are common in primary and secondary brain tumors, with symptoms varying as a function of tumor type, location, and size.
Objective:
The author presents a case of a 49-year-old woman with melanoma metastatic to the brain, in an effort to link lesions and complex olfactory and visual hallucinations.
Method:
The patient's history and clinical diagnostic procedures are presented.
Results:
A computerized tomographic scan showed lesions in the right parietal lobe, bilateral ring enhancing lesions, an enhancing lesion in the frontal lobes, and another lesion in the left temporal lobe.
Discussion:
The author discusses possible causal connections among lesions found and various complex symptoms.
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