Related Experiment Video
Updated: Jun 12, 2026

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
Published on: April 12, 2019
Characterizing proton relaxation times for metallic and magnetic layer-by-layer-coated, DNA-templated nanoparticle
Hamsa Jaganathan1, Richard L Gieseck, Albena Ivanisevic
1Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47906, USA.
Abstract:
Metallic and superparamagnetic DNA-templated nanoparticle (NP) chains are examined as potential imaging agents. Proton relaxation times (T(1) and T(2)) are measured for DNA nanostructures using nuclear magnetic resonance (NMR) spectroscopy. The layer-by-layer (LBL) method was used to encapsulate the DNA-templated NP chains and demonstrated a change in proton relaxation times. Results from this study suggest that LBL-coated, DNA-templated nanostructures can serve as effective imaging agents for magnetic resonance imaging (MRI) applications.

