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[Retroperitoneal mixed type liposarcoma: a case report].

T Yamaguchi1, H Suzuki, N Ishii

  • 1Department of Urology, Yamagata University School of Medicine.

Hinyokika Kiyo. Acta Urologica Japonica
|February 1, 1991
PubMed
Summary

Primary retroperitoneal tumors are rare, with liposarcomas comprising a small subset. This case highlights a large mixed-type liposarcoma, emphasizing the importance of surgical intervention and potential for metastasis in retroperitoneal malignancies.

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Area of Science:

  • Oncology
  • Surgical Pathology

Background:

  • Primary retroperitoneal tumors represent a rare group of malignancies, accounting for approximately 0.2% of all cancer diagnoses.
  • Liposarcomas constitute a significant proportion, estimated at 10-20%, of primary retroperitoneal tumors.
  • Mixed-type liposarcomas are particularly uncommon, making up 13.8% of reported retroperitoneal liposarcomas in previous Japanese literature.

Observation:

  • A 50-year-old male presented with a large left abdominal mass.
  • Imaging revealed a huge, hypovascular retroperitoneal tumor lacking discernible fat tissue.
  • The tumor was surgically excised en bloc with the left kidney due to encapsulation.

Findings:

  • Histopathological examination confirmed the diagnosis of a mixed-type liposarcoma.
  • The resected tumor measured 28 x 18 x 12 cm and weighed 3,100 g.

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  • Adjuvant therapy with OK-432 was administered post-operatively.

    • Implications:

    • Despite surgical management, the patient developed vertebral bone metastasis within 11 months and subsequent lung metastasis.
    • This case underscores the aggressive potential and metastatic capacity of mixed-type retroperitoneal liposarcomas.
    • Further research into effective adjuvant therapies and long-term management strategies for these rare tumors is warranted.