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Oriental cholangiohepatitis: pathologic, clinical, and radiologic features.

J H Lim1

  • 1Department of Diagnostic Radiology, Kyung Hee University Hospital, Seoul, Korea.

AJR. American Journal of Roentgenology
|July 1, 1991
PubMed
Summary

Oriental cholangiohepatitis causes recurrent pain, fever, and jaundice due to bile duct stones and inflammation. Imaging reveals characteristic ductal dilation and strictures, aiding diagnosis of this Southeast Asian endemic disease.

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Area of Science:

  • Hepatology
  • Gastroenterology
  • Radiology

Background:

  • Oriental cholangiohepatitis is endemic in Southeast Asia.
  • It presents with recurrent abdominal pain, fever, and jaundice.
  • Pathology includes dilated bile ducts with pigmented stones and pus, bile duct proliferation, and inflammation.

Purpose of the Study:

  • To describe the pathological and imaging findings of Oriental cholangiohepatitis.
  • To highlight characteristic features on sonography, CT, and cholangiography.

Main Methods:

  • Review of pathological findings.
  • Analysis of sonographic, CT, and cholangiographic features.

Main Results:

  • Pathology shows bile duct dilation, pigmented stones, pus, ductal proliferation, and inflammation.

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  • Imaging reveals intra- or extrahepatic duct stones, disproportionate extrahepatic duct dilation, localized intrahepatic duct dilation, and strictures.
  • Specific findings include increased periportal echogenicity, hepatic atrophy, and characteristic cholangiographic changes.

    • Conclusions:

    • Oriental cholangiohepatitis has distinct pathological and imaging features.
    • Imaging modalities like ultrasound, CT, and cholangiography are crucial for diagnosis.
    • The etiology remains unclear, with suggested associations with parasitic infections and nutritional factors.