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Updated: Jun 12, 2026

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion
Published on: February 24, 2021
Application of platelet-rich plasma in maxillofacial surgery: clinical evaluation
Pietro Gentile1, Davide J Bottini, Diana Spallone
1Department of Plastic and Reconstructive Surgery, University of Rome Tor Vergata, Rome, Italy. pietrogentile2004@libero.it
Abstract:
The authors report their experience on 15 cases, including reconstructive surgery of the jaws, postextraction alveolar bone regeneration, and oral implantology. The aim of the study was to evaluate the different effects on jaws' bone regeneration with or without the use of local application of platelet-rich plasma (PRP). The results we report showed the efficacy of the PRP treatment: postoperative patients' satisfaction and low-morbidity course confirmed the quality of the results. The article will help the reader to (1) understand the PRP preparation, (2) find local applications in oral and maxillofacial surgery, and (3) evaluate the general effect of PRP.
