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Updated: Jun 12, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Celiac disease (gluten-sensitive enteropathy).

¹Department of Medicine (Gastroenterology), University of British Columbia, Vancouver, BC, Canada. hugfree@shaw.ca

Minerva Gastroenterologica E Dietologica

|May 21, 2010

Summary

This summary is machine-generated.

Celiac disease is a gluten-dependent intestinal disorder causing malabsorption. Accurate diagnosis requires biopsy and response to a gluten-free diet, with challenges arising from adherence or misdiagnosis.

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Basic Three-Dimensional (3D) Intestinal Model System with an Immune Component

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

Basic Three-Dimensional (3D) Intestinal Model System with an Immune Component

Basic Three-Dimensional (3D) Intestinal Model System with an Immune Component

Published on: September 1, 2023

Area of Science:

Gastroenterology
Immunology
Internal Medicine

Background:

Celiac disease is a gluten-dependent small intestinal mucosal disorder affecting all age groups.
It leads to nutrient malabsorption, commonly presenting with diarrhea and weight loss.
Diagnosis relies on proximal small bowel biopsy findings and confirmed response to a gluten-free diet.

Purpose of the Study:

To review the diagnostic criteria and challenges in celiac disease management.
To explore reasons for persistent symptoms or incorrect diagnoses in patients with suspected celiac disease.
To discuss potential complications and differential diagnoses.

Main Methods:

Review of diagnostic approaches for celiac disease.
Analysis of factors contributing to recurrent symptoms or treatment failure.
Discussion of differential diagnoses and complications.

Main Results:

Recurrent symptoms often stem from poor gluten-free diet adherence or unrecognized gluten exposure.
Differential diagnoses include Crohn's disease, collagenous colitis, and functional bowel disease.
Rare complications like collagenous sprue and lymphoma can occur, particularly in sprue-like intestinal disorders.

Conclusions:

Accurate diagnosis and strict gluten-free diet adherence are crucial for managing celiac disease.
Persistent symptoms warrant re-evaluation for adherence, misdiagnosis, or alternative conditions.
Sprue-like intestinal disorders, including unclassified sprue, require careful monitoring for potential complications such as lymphoma.