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Updated: Jun 12, 2026

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
Published on: December 9, 2015
Legal developments and practical implications of gene patenting on targeted drug discovery and development
1Molecular Oncology, Blood Center of Wisconsin, Milwaukee, Wisconsin, USA. roger.klein@bcw.edu
Abstract:
The use of genetic information to design and guide therapies creates novel patent issues. Gene patents have been integral to the introduction of new biologics, but their role in diagnostic testing is controversial. Genotype-phenotype associations are at the heart of personalized medicine. The intellectual property rules by which these biological relationships are governed have profound implications for the growth of this field. Several cases currently before the courts may add reason and clarity to the law in this area.
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