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Dialyser reprocessing with Renalin.

S J Fleming1, K Foreman, K Shanley

  • 1Department of Renal Medicine, Royal Brisbane Hospital, Herston, Australia.

American Journal of Nephrology
|January 1, 1991
PubMed
Summary
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Renalin effectively reprocessed dialysers for hemodialysis reuse, achieving an average of 4.5 uses without compromising patient safety or key clearances. This method also preserved blood pressure and reduced symptoms, resulting in significant cost savings.

Area of Science:

  • Nephrology
  • Biomedical Engineering
  • Clinical Medicine

Background:

  • Dialyser reuse is a common practice to reduce healthcare costs.
  • Effective reprocessing agents are crucial for ensuring patient safety and treatment efficacy.
  • Renalin is a chemical agent used for disinfecting and reprocessing hemodialysis dialysers.

Purpose of the Study:

  • To evaluate the efficacy and safety of the dialyser reprocessing agent Renalin.
  • To assess the impact of Renalin-based dialyser reuse on patient outcomes and cost-effectiveness.

Main Methods:

  • A 6-month prospective study involving 2,759 hemodialysis sessions across 59 patients.
  • Dialysers were reused up to a maximum of 6 times.
  • Evaluation of dialyser survival, in vivo clearances (urea, creatinine, phosphate), and ultrafiltration characteristics.

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  • Monitoring for adverse events and patient symptoms.

    • Main Results:

    • Average dialyser reuse rate of 4.5 uses, with variations based on dialyser type.
    • No significant alteration in in vivo clearances of urea, creatinine, and phosphate after reuse.
    • A minor decrease in ultrafiltration characteristics observed with reused dialysers.
    • No clinically significant adverse events linked to dialyser reuse.
    • Improved blood pressure preservation and significantly fewer intradialytic symptoms in patients using reused dialysers.
    • Cost savings exceeding A 25,000 were achieved.

    Conclusions:

    • Renalin is a safe and effective agent for dialyser reprocessing, enabling multiple reuses.
    • Dialyser reuse with Renalin does not compromise essential clearance functions and may improve patient tolerance.
    • The practice leads to substantial cost savings in hemodialysis treatment.