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Updated: Jun 12, 2026
Orthotopic Liver Transplantation in Rats
Published on: July 1, 2012
Rapid and homogeneous reperfusion as a risk factor for postreperfusion syndrome during orthotopic liver
Lucas Cordoví de Armas1, Rosa E Jiménez Paneque, Boris Gala López
1Serviço de Anestesiologia, Hospital Clínico Quirúrgico Heramanos Ameijeiras. lucas@infomed.sld.cu
Background And Objectives:
The revascularization of the graft remains as a crucial instant of the orthotopic liver transplantation (OLT) surgical procedure. About a third of the recipients suffer the postreperfusion syndrome (PRS), a combination of hypothermia, metabolic disorders and cardiovascular instability potentially leading to cardiac arrest. The objective of this study was to evaluate the speed-quality (SQR) of the graft;s reperfusion as an independent predictor of PRS.
Methods:
All eligible patients receiving an OLT in our institution from 1987 to march 2009 were included. The adjusted OR for SQR-PRS association was obtained by means of logistic regression modeling including eight potential confounders.
Results:
The proportion of recipients suffering PRS was highest when the SQR was identified as good (75.8%) compared to those with middle or poor SQR; the relative risk comparing good SQR with poor SQR was 12.9 (CI 95%: 2.1-528.8). The adjusted OR was 132.9 (95% CI: 10.5-1688.6) when comparing good with bad SQR and 90.9 (95% CI: 13.8-645.2) when comparing good with intermediate SQR.
Conclusions:
According to our results, SQR can be considered an unambiguous predictor of PRS.
