Related Experiment Video
Updated: Jun 12, 2026
Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
[Meta analysis on effect of local application of chlorhexidine with scaling and root planing]
Li Lin1, Xiao-yan Li, Li-yun Liang
1Department of Periodontology, School of Stomatology,China Medical University, Shenyang 110002, Liaoning Province, China. linli_74k@yahoo.com
Purpose:
Meta analysis was used to assess the effect of local drug delivery system of chlorhexidine (CHX) as an adjunct to scaling and root planing(SRP) versus SRP alone in patients with chronic periodontitis.
Methods:
The selected studies of randomized controlled trials(RCTs) were pooled from six major electronic database up to May,2009 as CHX plus SRP versus SRP with at least 3 months of follow-up. Several English full texts were hand searched. Outcome measures were probing depth(PD) reduction and clinical attachment level (CAL)gain.
Results:
Seven studies that met inclusion criteria were entered into the Meta analysis. A significant mean reduction of PD in patients with CHX plus SRP was observed, but there were no significant difference in CAL between the two treatment groups.
Conclusions:
Chlorhexidine as an adjunct to SRP could reduce probing depth in the treatment of chronic periodontitis. Supported by Research Project of Education Bureau of Liaoning Province(Grant No.20061021).
Related Concept Videos
01:23Hand hygiene
Hand washing...
01:29Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
01:23Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...