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Related Experiment Video

Updated: Jun 12, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Sofa dermatitis presenting as a chronic treatment resistant dermatitis.

M Lynch1, P Collins

  • 1Dermatology Dept, St Vincent's University Hospital, Elm Park, Dublin 4. lynchmaeve@yahoo.ie

Irish Medical Journal
|May 22, 2010
PubMed
Summary

Sofa dermatitis cases have increased since 2007 due to allergic reactions to dimethyl fumarate. This report details a patient with a two-year history of persistent, treatment-resistant dermatitis linked to this allergen.

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Area of Science:

  • Dermatology
  • Allergology
  • Toxicology

Background:

  • A notable rise in sofa dermatitis cases has been observed globally since 2007.
  • This condition is increasingly associated with allergic contact sensitization.

Observation:

  • The primary causative agent identified is dimethyl fumarate (DMF).
  • DMF is recognized as a novel contact allergen.
  • This case involves a patient with a two-year history of dermatitis unresponsive to standard treatments.

Findings:

  • The patient's persistent dermatitis was directly linked to exposure to dimethyl fumarate.
  • Allergic contact sensitization to DMF was confirmed as the cause of the treatment-resistant rash.

Implications:

  • Highlights the importance of recognizing dimethyl fumarate as a significant contact allergen in consumer products.
  • Underscores the need for increased awareness among clinicians and the public regarding sofa dermatitis.
  • Suggests that environmental and consumer product exposure can lead to challenging dermatological conditions.