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Related Concept Videos

Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
Diversity of Protists II01:27

Diversity of Protists II

Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Diversity of Protists IV01:27

Diversity of Protists IV

Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...

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Related Experiment Video

Updated: Jun 12, 2026

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages
08:23

Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages

Published on: May 30, 2019

[Plasmodium knowlesi--the fifth species causing human malaria].

Anu Kantele1, Sakari Jokiranta

  • 1HUS/HYKS, Medisiininen tulosyksikkö, infektiosairauksien klinikka, HUS.

Duodecim; Laaketieteellinen Aikakauskirja
|May 22, 2010
PubMed
Summary

Plasmodium knowlesi, a fifth malaria species infecting humans, was identified in a Finnish tourist returning from Malaysia. This parasite, typically found in macaques, causes a disease severity between Plasmodium falciparum and other malaria species.

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Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

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Last Updated: Jun 12, 2026

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Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
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Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Published on: December 4, 2015

Area of Science:

  • Medical Parasitology
  • Infectious Diseases
  • Tropical Medicine

Context:

  • Human malaria is primarily caused by four Plasmodium species, with Plasmodium falciparum being the most severe.
  • A novel fifth species, Plasmodium knowlesi, typically infecting macaques, has emerged as a cause of human malaria.
  • Hundreds of human cases of P. knowlesi malaria have been reported in Malaysia since 2007.

Purpose:

  • To document the emergence and characteristics of Plasmodium knowlesi as a fifth cause of human malaria.
  • To compare the clinical severity of P. knowlesi malaria with other Plasmodium species.
  • To highlight diagnostic approaches for P. knowlesi infections.

Summary:

  • Plasmodium knowlesi, a simian malaria parasite, has been confirmed as a fifth species causing human malaria.
  • Clinical manifestations of P. knowlesi malaria are generally less severe than P. falciparum but more severe than other human malaria species.
  • Accurate diagnosis of P. knowlesi malaria relies on both Polymerase Chain Reaction (PCR) and microscopy.

Impact:

  • Recognizing P. knowlesi as a fifth human malaria species is crucial for accurate diagnosis and patient management.
  • Increased awareness of P. knowlesi is essential for public health strategies in malaria-endemic and travel-associated regions.
  • This finding expands our understanding of zoonotic malaria transmission and its implications for global health security.