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Updated: Jun 12, 2026

Collecting Saliva and Measuring Salivary Cortisol and Alpha-amylase in Frail Community Residing Older Adults via Family Caregivers
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Salivary and free serum cortisol evaluation

Christopher Duplessis1, Dominick Rascona, Malford Cullum

  • 1Naval Medical Center Portsmouth, Portsmouth VA, USA.

Military Medicine
|May 22, 2010
PubMed
Summary

Salivary cortisol can estimate free serum cortisol in non-ICU patients. However, it is not recommended for intensive care unit (ICU) patients due to sample issues. This study highlights differences in diagnosing adrenal insufficiency using free versus total cortisol.

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