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Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
Published on: May 27, 2022
YKL-40 expression in traumatic brain injury: an initial analysis
Dafna Bonneh-Barkay1, Pavel Zagadailov, Huichao Zou
1Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA. bonnehbarkayd@upmc.edu
Journal of Neurotrauma
|May 22, 2010
Abstract:
YKL-40 (chitinase 3-like protein 1) is expressed in a broad spectrum of inflammatory conditions and cancers. We have previously reported that YKL-40 levels are elevated in the cerebrospinal fluid (CSF) of macaques and humans with lentiviral encephalitis, as well as multiple sclerosis (MS). The current study assessed temporal CSF YKL-40 levels in subjects with severe traumatic brain injury (TBI; Glasgow Coma Scale [GCS] score

