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Related Experiment Video

Updated: Jun 12, 2026

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration

Published on: August 7, 2019

An assessment of fine-needle sampling techniques.

Puneet Titoria¹, Thiru M Siva, Tass Malik

¹Department of Otolaryngology, Torbay Hospital, Torquay, UK. puneet@titoria.com

Annals of the Royal College of Surgeons of England

|May 22, 2010

Summary

Multiplanar sampling techniques significantly increase tissue yield during fine-needle aspiration (FNA) procedures. This method optimizes sample collection for improved diagnostic accuracy in cytology.

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Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies

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Published on: September 29, 2009

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Last Updated: Jun 12, 2026

Detection of Extravascular Trypanosoma Parasites by Fine Needle Aspiration

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Use of Electromagnetic Navigational Transthoracic Needle Aspiration (E-TTNA) for Sampling of Lung Nodules

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Published on: May 23, 2015

Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies

Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies

Published on: September 29, 2009

Area of Science:

Medical Diagnostics
Surgical Pathology

Background:

Fine-needle cytology (FNC) is a sensitive and specific diagnostic tool.
Adequate sampling is crucial for accurate tissue-type diagnosis.
Interoperator variability and maximizing tissue yield are key challenges in FNC.

Purpose of the Study:

To explore sampling techniques to reduce interoperator variability.
To ensure maximal tissue yield in fine-needle sampling.
To compare the efficacy of different sampling methods.

Main Methods:

Apple cortical tissue was used as a proxy for human lymph node sampling.
Four distinct sampling methods were employed, with 50 samples per method.
Blue venepuncture needles were used, and samples were weighed to assess tissue yield.

Main Results:

One-way ANOVA and Tukey's HSD test were used for analysis.
Straight lance and coring techniques yielded comparable tissue mass (P > 0.05).
The multiplanar technique resulted in a significantly greater tissue yield (P < 0.05).

Conclusions:

Multiplanar sampling enhances tissue mass yield in fine-needle procedures.
Coring techniques do not appear to significantly impact tissue yield.
Optimizing sampling technique is vital for improving FNC efficacy.