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Probing Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices via Laser Flash Photolysis of Photoactivatable Nicotine
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Acetylcholine and choline acetyltransferase.

H G Mautner1

  • 1Dept. of Biochemistry and Pharmacology, Tufts Univ. School of Med., Boston, Mass., USA 02111.

Neurochemistry International
|May 22, 2010
PubMed
Summary

This study explores the alcoholysis of thiolesters and its relation to choline acetyltransferase. Key findings include the role of imidazole and an active-site arginine in enzyme function and substrate binding.

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