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Related Concept Videos

Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
Renal Failure: Dose Adjustments01:11

Renal Failure: Dose Adjustments

In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
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Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

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Related Experiment Videos

Renal complications in oncologic patients.

Melissa L Givens1, Joy Crandall

  • 1Department of Emergency Medicine, Carl R. Darnall Army Medical Center, 36000 Darnall Loop, Fort Hood, TX 76544, USA. melissa.givens@us.army.mil

Hematology/Oncology Clinics of North America
|May 22, 2010
PubMed
Summary

Acute renal failure (ARF) is a serious complication in cancer patients. This review details unique kidney injury causes in oncology, including tumor lysis syndrome (TLS) and thrombotic microangiopathy (TMA).

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Area of Science:

  • Nephrology
  • Oncology

Background:

  • Acute renal failure (ARF) is a significant complication in patients with malignancy.
  • Kidney injury in cancer patients often indicates a poorer prognosis.
  • Multiple factors can lead to renal insult in the oncologic setting.

Purpose of the Study:

  • To review common and unique causes of ARF in cancer patients.
  • To highlight specific oncologic emergencies like tumor lysis syndrome (TLS) and thrombotic microangiopathy (TMA).
  • To inform clinicians about these distinct renal threats.

Main Methods:

  • Literature review of oncologic complications and renal failure.
  • Focus on specific etiologies of kidney injury in malignancy.
  • Discussion of tumor lysis syndrome (TLS) and thrombotic microangiopathy (TMA) mechanisms.

Main Results:

  • Malignancy is associated with various causes of ARF.
  • Tumor lysis syndrome (TLS) presents a unique risk of acute kidney injury.
  • Thrombotic microangiopathy (TMA) is another critical cause of renal failure in cancer.

Conclusions:

  • ARF is a critical concern in oncology with significant prognostic implications.
  • Understanding specific etiologies like TLS and TMA is vital for timely diagnosis and management.
  • Early recognition and intervention are key to improving outcomes for cancer patients with renal complications.