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Published on: June 21, 2024
Ultrasound detection of vesicoureteral reflux in children
Gregor Novljan1, Tanja Kersnik Levart, Damjana Kljucevsek
1Department of Pediatric Nephrology and Pediatric Radiology Unit (DK, AK), University Medical Center, Ljubljana, Slovenia. gregor.novljan@mf.uni-lj.si
Insights
Voiding urosonography is a safe and reliable ultrasound technique for detecting vesicoureteral reflux in children. It offers reduced radiation exposure compared to traditional methods, with indirect techniques showing promise.
Area of Science:
- Pediatric Urology
- Diagnostic Imaging
- Medical Ultrasound
Background:
- Urinary tract infections (UTIs) are common in children and can be linked to vesicoureteral reflux (VUR).
- Current guidelines lack consensus on optimal investigation strategies after a child's first UTI.
- Minimally invasive imaging with low radiation exposure is preferred for pediatric patients.
Purpose of the Study:
- To evaluate various ultrasound techniques for detecting VUR in children.
- To emphasize the role and clinical relevance of voiding urosonography (VUS).
- To explore methods for VUR detection that avoid bladder catheterization.
Main Methods:
- Review of current literature and internal study results on VUS.
- Application of ultrasound techniques, including echo-enhancing agents, for improved VUR visualization.
- Development of indirect VUS and ureteral jet Doppler waveform analysis to avoid intravesical contrast agents.
Main Results:
- Echo-enhancing agents significantly improve ultrasound visualization of VUR.
- Indirect VUS and ureteral jet Doppler analysis show potential for detecting VUR without bladder catheterization.
- Sonomorphological features aid in VUR detection via ultrasound.
Conclusions:
- Voiding urosonography is a safe and reliable method for detecting VUR in children.
- VUS significantly reduces radiation exposure compared to conventional cystography methods.
- Indirect VUS and ureteral jet Doppler analysis may serve as non-invasive alternatives to voiding cystography, particularly in children over three years old.
Purpose:
We present different ultrasound techniques to detect vesicoureteral reflux in children with special emphasis on voiding urosonography.
Materials And Methods:
Urinary tract infection is a common problem in children that may be related to vesicoureteral reflux. Currently there is no consensus on investigations in children after the first urinary tract infection. The least invasive imaging with the smallest radiation burden should be used in children. Ultrasound to detect reflux meets several of these criteria. The development of echo enhancing agents has markedly improved reflux visualization by ultrasound.
Results:
We discuss the clinical relevance of voiding urosonography. We reviewed the currently available literature and the results of our studies of this issue. We also describe our endeavors to avoid catheterization and detect vesicoureteral reflux based on various sonomorphological features, ie indirect voiding urosonography and ureteral jet Doppler waveform analysis, to avoid applying any substance into the bladder.
Conclusions:
Voiding urosonography is safe and reliable to detect vesicoureteral reflux. When indicated, considerably decreased radiation exposure can be achieved by voiding urosonography instead of established cystography methods. Indirect voiding urosonography and ureteral jet Doppler waveform analysis could be an alternative to invasive voiding cystography, at least in children older than 3 years.
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