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Breakthrough pain: progress in management
Dominique A Lossignol1, Cristina Dumitrescu
1Pain Clinic, Institut Jules Bordet, Brussels, Belgium. dominique.lossignol@bordet.be
Current Opinion in Oncology
|May 22, 2010
Summary
Recent developments in cancer breakthrough pain (BTP) treatment highlight fentanyl
Area of Science:
- Oncology
- Pain Management
- Pharmacology
Background:
- Breakthrough pain (BTP) in cancer patients is often underdiagnosed and undertreated.
- Unique physiopathology and clinical significance necessitate specific treatment considerations.
Purpose of the Study:
- To review recent advancements in the management of cancer breakthrough pain (BTP).
- Focus on the latest literature and developments in BTP treatment.
Main Methods:
- Literature review using Medline database.
- Analysis of recent publications on cancer breakthrough pain.
Main Results:
- Fentanyl (oral or nasal) is the preferred agent for BTP management.
- Ongoing research aims to enhance fentanyl's efficacy, safety, and pharmacokinetic profile.
- BTP remains a significant challenge in cancer care.
Conclusions:
- Accurate diagnosis and targeted treatment are crucial for effective BTP relief in cancer patients.
- Continued research is vital for improving BTP management strategies.
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