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Related Experiment Video

Updated: Jun 12, 2026

A Free-breathing fMRI Method to Study Human Olfactory Function

A Free-breathing fMRI Method to Study Human Olfactory Function

Published on: July 30, 2017

Migraine and olfactory stimuli.

Christina Sjöstrand¹, Ivanka Savic, Eva Laudon-Meyer

¹Headache Research Centre, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden. christina.sjostrand@ki.se

Current Pain and Headache Reports

|May 22, 2010

Summary

This summary is machine-generated.

Migraine patients frequently experience odour intolerance and olfactory hypersensitivity. This study confirms this common feature in women with migraine, linking it to migraine pathophysiology.

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Area of Science:

Neuroscience
Ophthalmology
Sensory Science

Background:

Migraine patients commonly report odour intolerance.
Osmophobia (fear of smells) occurs during migraine attacks.
Olfactory hypersensitivity is reported between attacks.

Purpose of the Study:

To explore olfactory mechanisms in migraine.
To investigate odour intolerance and hypersensitivity in migraineurs.
To present findings from a pilot study on olfactory sensitivity in women with migraine.

Main Methods:

Literature review of olfactory mechanisms in migraine.
Pilot questionnaire study in young women diagnosed with migraine.

Main Results:

Pilot study confirmed olfactory hypersensitivity is common in women with migraine.
Findings support a link between odour intolerance and migraine pathophysiology.

Conclusions:

Olfactory hypersensitivity is a significant feature in migraine.
Migraine pathophysiology likely contributes to odour intolerance.
Further research into odour-related mechanisms in migraine is warranted.