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Updated: Jun 12, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Stroke in Women: What is Different?
Dara G Jamieson1, Maryna Skliut
1Department of Neurology and Neuroscience, New York Presbyterian Hospital, Weill Cornell Medical College of Cornell University, NY 10065, USA. dgj2001@med.cornell.edu
Current Atherosclerosis Reports
|May 22, 2010
Summary
Stroke incidence and outcomes differ between men and women. While boys have more strokes than girls, women over 80 experience higher rates. Women face unique risks and poorer outcomes post-stroke compared to men.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Stroke is a leading cause of death and disability globally.
- Significant disparities exist in stroke incidence and outcomes between sexes and across age groups.
- Understanding these sex- and gender-related differences is crucial for effective prevention and treatment.
Purpose of the Study:
- To analyze the age- and sex-specific incidence of stroke.
- To explore the underlying reasons for observed differences in stroke occurrence and outcomes.
- To compare stroke risk and response to treatment in women versus men.
Main Methods:
- Review of epidemiological data on stroke incidence across different demographics.
- Analysis of factors contributing to sex- and gender-related variations in stroke.
- Comparison of primary and secondary stroke prevention strategies and treatment responses.
Main Results:
- Boys experience higher stroke incidence than girls.
- Stroke incidence rises in men during their 60s and 70s, and in women after age 80.
- Women have a higher lifetime risk of stroke than myocardial infarction and generally experience poorer outcomes despite similar thrombolysis response.
Conclusions:
- Hormonal and lifestyle factors contribute to sex- and gender-based differences in stroke.
- Women's unique risk factors and later-life stroke prevalence necessitate tailored prevention and care.
- Older women with stroke, often presenting with more severe cases, face worse prognoses.
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