Related Experiment Video

Updated: Jun 12, 2026

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
04:14

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults

Published on: February 28, 2025

Clinico-pathological spectrum of gallbladder disease in children

R P S Punia1, Shailja Garg, Bhumika Bisht

  • 1Department of Pathology and General Surgery, Government Medical College & Hospital, Chandigarh, India. drpunia@gmail.com

Acta Paediatrica (Oslo, Norway : 1992)
|May 25, 2010
PubMed

Insights

Gallstone disease in children is rare, affecting 0.79% of those undergoing gallbladder removal. Non-hemolytic gallstones are more common than hemolytic types in this Indian region.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Hepatobiliary Diseases

Background:

  • Gallbladder disease in children exhibits significant global variation.
  • Understanding regional clinico-pathological patterns is crucial for effective management.

Purpose of the Study:

  • To analyze the clinico-pathological spectrum of gallbladder disease in children.
  • To determine the frequency and characteristics of gallstone disease in a pediatric population within a specific Indian region.

Main Methods:

  • Retrospective review of pediatric patients who underwent cholecystectomy.
  • Data collected over an 8-year period (January 2002 - December 2009).
  • Analysis of patient demographics, clinical presentation, surgical findings, and histopathological results.

Main Results:

  • Gallbladder disease was found in 0.79% of pediatric cholecystectomies (56 out of 7076).
  • The majority of affected children (69.6%) were aged 11-16 years, with a higher prevalence in girls (66.07%).
  • Acalculous cholecystitis occurred in 21.4% of cases; 8.9% had associated hemolytic disease, and 7.1% had congenital anomalies like choledochal cysts. Mixed cholelithiasis was the most common type (39.3%).

Conclusions:

  • The incidence of gallstone disease in children in this region is 0.79%.
  • Non-hemolytic cholelithiasis is more prevalent than the hemolytic type.
  • An unusual case of cysticercus in the gallbladder wall was identified, highlighting diagnostic diversity.
Abstract

Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...