Related Experiment Video
Updated: Jun 12, 2026

08:49
External Cephalic Version: Is it an Effective and Safe Procedure?
Published on: June 6, 2020
Maternal mortality and cesarean delivery: an analytical observational study
Gourisankar Kamilya1, Subrata Lall Seal, Joydev Mukherji
1Department of Obstetrics and Gynaecology, R. G. Kar Medical College, Kolkata, India. drgkamilya@gmail.com
The Journal of Obstetrics and Gynaecology Research
|May 25, 2010
Summary
Cesarean delivery (CD) significantly increases maternal mortality risk by 3-fold compared to vaginal delivery (VD). The risk is especially high for intrapartum CD, underscoring the need for cautious application of cesarean birth.
Area of Science:
- Obstetrics and Gynecology
- Maternal Health
- Surgical Outcomes
Background:
- Understanding maternal mortality risks associated with delivery methods is crucial for pregnant women and clinicians.
- Existing literature often lacks robust study designs and sufficient power to definitively link maternal mortality to delivery mode.
- Cesarean delivery (CD) is increasingly viewed as a low-risk procedure, necessitating a re-evaluation of its associated risks.
Purpose of the Study:
- To evaluate the intrinsic risk of maternal death directly attributed to cesarean delivery (CD) compared to vaginal delivery (VD).
- To further assess the differential risks associated with antepartum (before labor) and intrapartum (during labor) CD.
- To provide evidence-based insights for clinical decision-making regarding delivery modes.
Main Methods:
- A retrospective cohort study analyzing deliveries, excluding those with medical or obstetric comorbidities.
- Comparison of maternal mortality rates between surviving mothers who underwent CD and those who underwent VD.
- Collection of clinical information for all maternal deaths during the study period.
Main Results:
- Cesarean delivery was associated with a 3.01-fold increased risk of maternal mortality compared to vaginal delivery.
- The risk of maternal death was significantly higher for intrapartum CD (OR 4.86) than for antepartum CD (OR 1.73).
- Increased risks of death were observed from anesthesia complications, puerperal infection, and venous thromboembolism; postpartum hemorrhage risk did not differ significantly.
Conclusions:
- Cesarean delivery carries a significantly higher risk of maternal death than vaginal delivery.
- The risk of maternal mortality is particularly elevated when cesarean delivery is performed during labor.
- Cesarean delivery should be reserved for situations with clear medical or obstetric indications.
Related Concept Videos
Development of the Oral Microbiota
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Statistical Methods for Analyzing Epidemiological Data
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
Regression Toward the Mean
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...

