Related Experiment Video
Updated: Aug 17, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Effect of sulindac on the cough reflex of healthy subjects
G Foster1, W W Yeo, L E Ramsay
1University Department of Medicine and Pharmacology, Royal Hallamshire Hospital, Sheffield.
Abstract:
The effects of a single dose of sulindac 200 mg and placebo on the capsaicin-induced cough reflex were studied in a two-phase double-blind crossover study in 18 healthy subjects. Sulindac increased the threshold for capsaicin cough response significantly, but did not alter D5, peak response, or the total cough response when compared with placebo values.
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