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Published on: November 5, 2019
Human meningitis from Streptococcus equi subsp. zooepidemicus acquired as zoonoses
L R Minces1, P J Brown, P J Veldkamp
1Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. mincesL2@upmc.edu
Abstract:
Streptococcus equi subsp. zooepidemicus rarely causes meningitis in humans by contact with domestic animals or their unpasteurized products. In this paper we reviewed the literature pertaining to the epidemiological and clinical aspects relating to this infection on previously reported cases of human disease. Additionally, the case of a 51-year-old female who acquired meningitis with this organism after contact with a horse is described. This patient was successfully treated with ceftriaxone, yet penicillin remains the treatment of choice. This aetiological agent should be considered in the proper epidemiological context.
Insights
Streptococcus equi subsp. zooepidemicus can cause rare human meningitis, often linked to animal contact. Prompt diagnosis and treatment, typically with penicillin, are crucial for recovery.
Area of Science:
- Zoonotic diseases
- Bacterial meningitis
- Veterinary epidemiology
Background:
- Streptococcus equi subsp. zooepidemicus is a bacterium primarily associated with horses.
- Human infections are rare but can occur through direct contact with infected animals or contaminated products.
- Meningitis is a serious infection of the membranes surrounding the brain and spinal cord.
Observation:
- A case study of a 51-year-old female who developed meningitis after horse contact is presented.
- The patient was successfully treated with ceftriaxone.
- Literature review on epidemiological and clinical aspects of human Streptococcus equi subsp. zooepidemicus infections.
Findings:
- Streptococcus equi subsp. zooepidemicus meningitis in humans is an uncommon but significant zoonotic disease.
- Penicillin is identified as the preferred treatment, although ceftriaxone can also be effective.
- Epidemiological context, including animal contact, is vital for diagnosing this infection.
Implications:
- Highlights the importance of considering zoonotic pathogens in meningitis cases, especially with relevant exposure history.
- Emphasizes the need for awareness among healthcare professionals regarding Streptococcus equi subsp. zooepidemicus as a potential human pathogen.
- Informs veterinary and public health strategies for preventing and managing rare zoonotic meningitis cases.
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Bacterial Meningitis I: Introduction
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