[Multiple Non-ossifying Fibroma (Case-report).]

The authors present the case-history of a patient with multiple non-ossifying fibroma causing pathological fractures in the long bones of the lower extremities, the vertebral bodies, ribs and bones of the brachial plexus. Since 1988 when the first pathological fracture occurred up to the present time when the tumour was found at other sites five biopsies of foci were made, all with the same histological finding. The pathological fracture in the distal portion of the right femur and the proximal portion of the left femur were treated by osteosynthesis and filled with bone cement. Subsequently in the case of the distal femur on the right side by resection of the distal end of the femur with an extensive tumour and by replacement with a transplant. A large focus in the proximal femur on the right was preventively filled with bone cement. As to tumorous foci in the vertebrae, skeleton of the upper extremities and ribs so far no action was taken. The authors discuss the histological picture and differential diagnosis of a non-ossifying osseous fibroma. Key words: metaphyseal fibrous defect, non-ossifying osseous fibroma, pathological fracture multiple occurrence.