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Updated: Jun 12, 2026

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
Published on: August 15, 2017
Changes of extracellular proteins in hippocampus during depolarization
B Nyström1, A Hamberger, J O Karlsson
1Institute of Neurobiology, University of Göteborg, Göteborg, Sweden.
Abstract:
Local excitation of the hippocampus with N- methyl- d,l -aspartic acid caused a rapid release of specific proteins into the extracellular fluid. The proteins were recovered from the effluent of a small implanted tubing, permeable to macromolecules, and analyzed by sodium dodecyl sulphate electrophoresis.
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