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Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
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A new P(II) protein structure identifies the 2-oxoglutarate binding site

Daphne Truan1, Luciano F Huergo, Leda S Chubatsu

  • 1Macromolecular Crystallography, Swiss Light Source, Villigen PSI, Switzerland.

Journal of Molecular Biology
|May 25, 2010
PubMed
Summary

The P(II) protein GlnZ structure reveals 2-oxoglutarate binds in a cleft between subunits, clarifying nitrogen metabolism regulation. This finding contrasts with prior studies and explains effector signal output.

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