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Updated: May 5, 2026

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
Vagal-sparing esophagectomy: is it a useful addition?
1Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA. sdemeester@surgery.usc.edu
Abstract:
A vagal sparing esophagectomy should be considered for patients with end-stage benign disease and Barrett's high-grade dysplasia or intramucosal adenocarcinoma. No lymphadenectomy is performed with this procedure, so it is not applicable to cancers invasive into the submucosa. Advantages of a vagal-sparing procedure over a standard esophagectomy with gastric pull-up include its simplicity to perform, ability to be done as a laparoscopic procedure, lack of requirement for single-lung ventilation or mediastinal dissection, avoidance of the need for a pyloroplasty, and preservation of the vagus nerves. Given these advantages, a vagal-sparing esophagectomy should be the preferred method of esophageal resection in appropriate patients.
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