Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COVID-19 and Neurologic Manifestations: An Experience at Major New York City Hospitals.

Cureus·2022
Same author

Point To Area of Pain: A Clinically Useful Telehealth Physical Exam Technique for Focal Nociceptive and Neuropathic Pain.

Pain physician·2022
Same author

Atypical Teratoid Rhabdoid Tumor: Two Case Reports and an Analysis of Adult Cases with Implications for Pathophysiology and Treatment.

Frontiers in neurology·2017
Same author

Poster 236 The Use of a Telepresence Communications Robot by a Patient with Spinal Cord Injury to Aid in Social Reintegration and "Virtual Mobility": A Case Report.

PM & R : the journal of injury, function, and rehabilitation·2016
Same author

Poster 324 Opsoclonus-Myoclonus-Ataxia Syndrome and HIV Infection. A Case Report.

PM & R : the journal of injury, function, and rehabilitation·2016
Same author

Poster 409 Tackling Pain After Above Knee Amputation: What Are Our Options? A Case Report.

PM & R : the journal of injury, function, and rehabilitation·2016

Related Experiment Video

Updated: Jun 12, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

Aging with multiple sclerosis.

Michelle Stern1, Lyssa Sorkin, Kelly Milton

  • 1Department of Physical Medicine and Rehabilitation, Columbia University College of Physicians and Surgeons, New York Presbyterian Hospital, 180 Fort Washington Avenue, Harkness Pavilion, Suite 199, NY 10032, USA. ms1127@columbia.edu <ms1127@columbia.edu>

Physical Medicine and Rehabilitation Clinics of North America
|May 25, 2010
PubMed
Summary
This summary is machine-generated.

Caring for aging adults with multiple sclerosis (MS) requires a comprehensive approach. Understanding disease and aging complications helps healthcare professionals minimize disability and improve patient outcomes.

More Related Videos

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
08:48

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

Published on: January 29, 2016

Related Experiment Videos

Last Updated: Jun 12, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
08:48

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

Published on: January 29, 2016

Area of Science:

  • Neurology
  • Geriatrics
  • Public Health

Background:

  • Multiple sclerosis (MS) is a chronic, progressive neurological disease.
  • It frequently affects young adults, leading to long-term disability.
  • Patients with MS often have near-normal lifespans, necessitating consideration of aging-related issues.

Purpose of the Study:

  • To highlight the importance of a comprehensive, multidisciplinary approach in managing multiple sclerosis.
  • To emphasize the need for healthcare professionals to understand the unique challenges faced by aging patients with MS.
  • To guide healthcare providers in minimizing morbidity and disability in this population.

Main Methods:

  • Literature review on multiple sclerosis and aging.
  • Analysis of potential disease and age-related complications.
  • Synthesis of best practices for multidisciplinary care.

Main Results:

  • Aging patients with MS face a complex interplay of disease progression and age-related health issues.
  • Proactive management of potential complications is crucial for maintaining quality of life.
  • A coordinated, patient-centered care plan is essential.

Conclusions:

  • Healthcare professionals must be aware of the dual challenges of MS and aging.
  • Minimizing morbidity and disability requires understanding and addressing these combined challenges.
  • Comprehensive care can significantly improve long-term outcomes for individuals with multiple sclerosis.