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Updated: Jun 12, 2026

Clinical Imaging of Microwave Mammography
Published on: November 14, 2025
Probably benign lesions detected on breast MR imaging
Peter R Eby1, Wendy B DeMartini, Robert L Gutierrez
1Department of Radiology, University of Washington School of Medicine, 1959 NE Pacific, Seattle, WA 98195, USA. preby@u.washington.edu
The BI-RADS 3 assessment category for breast MRI findings needs clearer definitions for "probably benign" lesions. This review guides radiologists on selecting lesions for short-term follow-up, aiming to reduce unnecessary biopsies.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- The Breast Imaging Reporting and Data System (BI-RADS) MRI atlas includes a 'probably benign' category.
- Short-term follow-up is often recommended for these lesions, but criteria are not well-defined.
Purpose of the Study:
- To review data on the BI-RADS 3 assessment category for breast MRI.
- To define characteristics of lesions suitable for short-term follow-up and reduce unnecessary biopsies.
Main Methods:
- Review of published retrospective and prospective data.
- Analysis of lesion morphology and kinetics for BI-RADS 3 suitability.
- Consideration of factors influencing BI-RADS 3 category use.
Main Results:
- The article reviews the cancer yield of the BI-RADS 3 category.
- It discusses lesion characteristics and factors affecting the use of BI-RADS 3.
- An algorithm with imaging examples is provided.
Conclusions:
- Further research is needed to define specific morphologic and kinetic characteristics for safe short-term follow-up.
- Clarifying these criteria can help patients avoid biopsy without altering prognosis.
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