Related Experiment Video
Updated: Jun 12, 2026
04:39
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Hashimoto encephalopathy with fulminant myocarditis.
Mark Podberezin1, Matthew N Meriggioli, Alberto Locante
1Department of Pathology, University of Illinois Medical Center at Chicago, Chicago, IL, USA.
Pathology, Research and Practice
|May 25, 2010
Summary
This study reports a rare case of autoimmune thyroiditis complicated by Hashimoto encephalopathy and autoimmune myocarditis. It suggests a potential shared mechanism between Hashimoto encephalopathy and myocarditis in some autoimmune thyroiditis patients.
Area of Science:
- Endocrinology
- Cardiology
- Neurology
Background:
- Limited data exist on lymphocytic thyroiditis and cardiomyopathy.
- Autoimmune thyroiditis is associated with various autoimmune conditions.
- Hashimoto encephalopathy (HE) is a rare neurological disorder linked to autoimmune thyroiditis.
Observation:
- A 31-year-old man with autoimmune thyroiditis presented with neurological and cardiac complications.
- The patient developed Hashimoto encephalopathy.
- The patient ultimately succumbed to autoimmune myocarditis.
Findings:
- This case highlights a potential association between autoimmune thyroiditis, Hashimoto encephalopathy, and autoimmune myocarditis.
- The co-occurrence of HE and myocarditis in this patient is unprecedented in published literature.
- This association suggests a possible shared pathogenetic pathway.
Implications:
- Further research is warranted to explore the link between autoimmune thyroiditis, HE, and myocarditis.
- Understanding shared mechanisms could lead to novel diagnostic or therapeutic strategies.
- This case underscores the systemic autoimmune potential of thyroiditis.
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