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Updated: Jun 12, 2026

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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
Published on: November 22, 2014
A unique protein labeling system based on melittin and the non-covalent binding-induced pyrene excimer
Yue Li1, Hong-Wei Li, Li-Jun Ma
1State Key Laboratory of Supramolecular Structure and Materials, Jilin University, No. 2699, Qianjin Street, Changchun, 130012, China.
Abstract:
We report a unique protein labeling system based on melittin and a pyrene derivative (1). The specific region of the C-terminal in melittin efficiently induced the formation of the pyrene eximer, which can be used as a tag to target proteins and for further detection.
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