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Stroke in patients with migraine

Jacques De Reuck1, Koen Paemeleire, Georges Van Maele

  • 1Department of Neurology, Ghent University Hospital, Belgium. dereuck.j@gmail.com

Neurologia I Neurochirurgia Polska
|May 25, 2010
PubMed
Abstract

Insights

Patent foramen ovale (PFO) is a significant risk factor for stroke in migraine patients, more so than migraine with aura (MA). This study found no direct link between MA and stroke, highlighting PFO as a key consideration.

Area of Science:

  • Neurology
  • Cardiology
  • Vascular Medicine

Background:

  • Migraine with aura (MA) is a suspected risk factor for ischemic stroke.
  • This study investigates the relationship between migraine and stroke, comparing patients with and without stroke.

Purpose of the Study:

  • To compare clinical characteristics and risk factors in migraine patients with and without stroke.
  • To identify potential risk factors for stroke in individuals with a history of migraine.

Main Methods:

  • Retrospective observational study comparing 14 migraine patients with stroke and 37 without.
  • Analysis of clinical data, vascular risk factors, and diagnostic imaging results.

Main Results:

  • Stroke occurred in both migraine with aura and without aura patients.
  • Patent foramen ovale (PFO) was identified as the primary risk factor for stroke in migraine patients.
  • Strokes were predominantly supratentorial, with good outcomes. White matter hyperintensities were more common in migraine patients with stroke.

Conclusions:

  • Patent foramen ovale (PFO), not migraine with aura (MA), is the main stroke risk factor in migraine patients.
  • A direct causal relationship between MA and stroke was not demonstrated in this study.

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