Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Menopause

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...

Disorders of the Male Reproductive System

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...

Aging

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

The Effect of Aging on Tissues

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...

Bone Disorders

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

Drug Dosing: Geriatric Patients

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Cannabidiol improves learning and memory deficits and alleviates anxiety in 12-month-old SAMP8 mice.

PloS one·2025

Same author

Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR).

The journal of nutrition, health & aging·2025

Same author

Gut microbiota disturbances in hospitalized older adults with malnutrition and clinical outcomes.

Nutrition (Burbank, Los Angeles County, Calif.)·2024

Same author

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation.

The Journal of biological chemistry·2023

Same author

Low circulating adropin levels in late-middle aged African Americans with poor cognitive performance.

npj aging·2023

Same author

Anorexia of aging: An international assessment of healthcare providers' knowledge and practice gaps.

Journal of cachexia, sarcopenia and muscle·2023

Search research articles

Related Experiment Video

Updated: Jun 12, 2026

Frailty Assessment in an Aging Mouse Model

Frailty Assessment in an Aging Mouse Model

Published on: September 23, 2025

Aging male.

Milta O Little¹, John E Morley

¹Division of Geriatric Medicine, Saint Louis University School of Medicine, 1402 South Grand Boulevard, M238, St Louis, MO 63104, USA.

Clinics in Geriatric Medicine

|May 26, 2010

Summary

This summary is machine-generated.

Physicians face unique challenges when treating older men. Recognizing these specific health issues is crucial for providing effective patient care and improving health outcomes.

Related Experiment Videos

Last Updated: Jun 12, 2026

Frailty Assessment in an Aging Mouse Model

Frailty Assessment in an Aging Mouse Model

Published on: September 23, 2025

Area of Science:

Geriatric Medicine
Men's Health

Background:

Older male patients present distinct physiological and psychosocial considerations.
Standard medical approaches may not fully address the complexities of aging in men.

Purpose of the Study:

To highlight the specialized issues encountered by physicians treating older men.
To underscore the importance of recognizing these challenges for optimal patient care.

Main Methods:

This article provides a review of the literature.
It synthesizes key considerations in geriatric male health.

Main Results:

Several unique challenges require physician attention.
These issues significantly impact the health and well-being of older male patients.

Conclusions:

Physicians must be aware of and address the specific needs of older male patients.
Attentive care to these unique challenges can lead to better health outcomes.