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DIALIGN-TX and multiple protein alignment using secondary structure information at GOBICS
Amarendran R Subramanian1, Suvrat Hiran, Rasmus Steinkamp
1Wilhelm-Schickard-Institut für Informatik, University of Tübingen, Sand 13, 72076 Tübingen, Germany.
Abstract:
We introduce web interfaces for two recent extensions of the multiple-alignment program DIALIGN. DIALIGN-TX combines the greedy heuristic previously used in DIALIGN with a more traditional 'progressive' approach for improved performance on locally and globally related sequence sets. In addition, we offer a version of DIALIGN that uses predicted protein secondary structures together with primary sequence information to construct multiple protein alignments. Both programs are available through 'Göttingen Bioinformatics Compute Server' (GOBICS).
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