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Measuring and improving adherence to osteoporosis pharmacotherapy
Suzanne M Cadarette1, Andrea M Burden
1Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada. s.cadarette@utoronto.ca
Current Opinion in Rheumatology
|May 26, 2010
Summary
Improving adherence to osteoporosis pharmacotherapy is crucial for reducing fracture risk. Strategies should focus on minimizing treatment gaps and personalizing interventions for better patient outcomes in osteoporosis management.
Area of Science:
- Bone Health and Osteoporosis Research
- Pharmacotherapy Adherence Studies
- Public Health and Fracture Prevention
Background:
- Osteoporosis poses a significant public health challenge, leading to substantial fracture-related morbidity.
- Despite effective treatments, suboptimal adherence to osteoporosis pharmacotherapy diminishes drug effectiveness.
- Understanding and improving patient adherence is critical for successful osteoporosis management.
Purpose of the Study:
- To review methods for measuring adherence to osteoporosis pharmacotherapy.
- To explore strategies for improving adherence to osteoporosis medications.
- To address the public health issue of suboptimal treatment persistence.
Main Methods:
- Literature review of adherence measurement techniques.
- Analysis of factors influencing patient persistence with osteoporosis drugs.
- Synthesis of evidence on interventions to improve pharmacotherapy adherence.
Main Results:
- A majority of patients discontinue osteoporosis pharmacotherapy, often reinitiating treatment after significant gaps.
- Reducing the frequency and duration of treatment gaps is key to enhancing adherence.
- Multifaceted, individualized interventions show promise for improving adherence rates.
Conclusions:
- Adherence to osteoporosis pharmacotherapy is characterized by low persistence and prolonged treatment gaps.
- Consistent communication about therapy importance and identifying at-risk patients are vital.
- Further research is needed for risk profiling, targeted interventions, and guidance on drug holidays.
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