[Chronic kidney diseases: common and harmful, but also preventable and treatable]

Marcus Gomes Bastos1, Rachel Bregman, Gianna Mastroianni Kirsztajn

  • 1Universidades - Universidade Federal de Juiz de Fora - MG, Universidade do Estado do Rio de Janeiro - UERJ e Universidade Federal de São Paulo - UNIFESP, São Paulo, SP.

Revista Da Associacao Medica Brasileira (1992)
|May 26, 2010
PubMed

Insights

Chronic kidney disease (CKD) is a growing global health issue. Early diagnosis and intervention can significantly delay complications and improve outcomes for CKD patients.

Area of Science:

  • Nephrology
  • Public Health
  • Epidemiology

Context:

  • Chronic kidney disease (CKD) presents a significant global public health challenge.
  • Brazil faces increasing incidence and prevalence of end-stage renal failure, with poor prognosis and high treatment costs.
  • CKD management is complex, with major outcomes including cardiovascular events, mortality, and progressive loss of kidney function.

Purpose:

  • To review the current definition and staging of CKD.
  • To discuss essential preventive measures for CKD.
  • To highlight the importance of early diagnosis and renoprotective/cardioprotective strategies.

Summary:

  • CKD complications encompass anemia, metabolic acidosis, malnutrition, and mineral metabolism alterations.
  • Cardiovascular disease remains a leading cause of death in CKD patients.
  • Early detection and timely implementation of renoprotective and cardioprotective treatments can postpone adverse outcomes.

Impact:

  • Early CKD diagnosis and management can significantly improve patient prognosis.
  • Implementing preventive measures can reduce the burden of CKD complications.
  • This review provides insights into optimizing CKD care through early intervention strategies.

Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...