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[Chronic kidney diseases: common and harmful, but also preventable and treatable]
Marcus Gomes Bastos1, Rachel Bregman, Gianna Mastroianni Kirsztajn
1Universidades - Universidade Federal de Juiz de Fora - MG, Universidade do Estado do Rio de Janeiro - UERJ e Universidade Federal de São Paulo - UNIFESP, São Paulo, SP.
Insights
Chronic kidney disease (CKD) is a growing global health issue. Early diagnosis and intervention can significantly delay complications and improve outcomes for CKD patients.
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Context:
- Chronic kidney disease (CKD) presents a significant global public health challenge.
- Brazil faces increasing incidence and prevalence of end-stage renal failure, with poor prognosis and high treatment costs.
- CKD management is complex, with major outcomes including cardiovascular events, mortality, and progressive loss of kidney function.
Purpose:
- To review the current definition and staging of CKD.
- To discuss essential preventive measures for CKD.
- To highlight the importance of early diagnosis and renoprotective/cardioprotective strategies.
Summary:
- CKD complications encompass anemia, metabolic acidosis, malnutrition, and mineral metabolism alterations.
- Cardiovascular disease remains a leading cause of death in CKD patients.
- Early detection and timely implementation of renoprotective and cardioprotective treatments can postpone adverse outcomes.
Impact:
- Early CKD diagnosis and management can significantly improve patient prognosis.
- Implementing preventive measures can reduce the burden of CKD complications.
- This review provides insights into optimizing CKD care through early intervention strategies.
Abstract:
Chronic kidney disease (CKD) is a public health problem worldwide. In Brazil incidence and prevalence of end stage renal failure are increasing; prognosis is still poor and costs of disease treatment are very high. Regardless of the etiology, main outcomes in patients with CKD are its complications (anemia, metabolic acidosis, malnutrition and alteration in mineral metabolism), death (mainly due to cardiovascular causes) and loss of renal function. Recent studies indicate that these outcomes may be postponed with specific treatment if the CKD is diagnosed early and renoprotective and cardioprotective measures are implemented early in the course of the disease. The current definition and staging of CKD, as well as the discussion of the main preventive measures are addressed in this review.
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