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Lung abscess in a child with Mycoplasma pneumoniae infection
Salvatore Leonardi1, Michele Miraglia del Giudice, Lucia Spicuzza
1Department of Pediatrics, University of Catania, Via S.Sofia 78, Catania, Italy. leonardi@unict.it
Abstract:
Mycoplasma pneumoniae is a common cause of community-acquired pneumonia in children, while lung abscess is a severe complication of bacterial pneumonias caused mainly by pyogenes. Here we report a previously healthy 10-year-old boy admitted to our unit for a right upper lobe pneumonia, with a 15-day history of fever and cough insensitive to oral amoxicillin and intramuscular ceftriaxone. Chest computed tomography scan revealed that the right upper lobe consolidation was an abscess and that a similar formation was present in the right mid region. Serology allowed the diagnosis of M. pneumoniae infection. The clinical picture rapidly improved after initiation of oral clarithromycin, and radiographic resolution, without sequelae, was observed after 1-month treatment. Lung abscess in children is a rare complication of M. pneumoniae infection and only three previous cases have been described in the literature, all associated with a delayed diagnosis and late initiation of macrolide therapy. A long-term treatment with oral macrolide allows a prompt recovery and restitution ad integrum of the lung.
Insights
Mycoplasma pneumoniae can cause lung abscesses in children, a rare but serious condition. Early diagnosis and macrolide treatment lead to full recovery without lasting lung damage.
Area of Science:
- Pediatrics
- Infectious Diseases
- Pulmonology
Background:
- Mycoplasma pneumoniae is a frequent cause of childhood pneumonia.
- Lung abscess is a severe complication typically linked to bacterial pneumonias.
Observation:
- A previously healthy 10-year-old boy presented with persistent pneumonia symptoms unresponsive to antibiotics.
- Computed tomography revealed lung abscesses in the right upper and mid regions.
- Diagnosis of Mycoplasma pneumoniae infection was confirmed via serology.
Findings:
- The patient showed rapid clinical improvement after initiating oral clarithromycin.
- Complete radiographic resolution of lung abscesses was achieved after one month of treatment.
- This case highlights lung abscess as a rare complication of Mycoplasma pneumoniae.
Implications:
- Early diagnosis and macrolide therapy are crucial for managing Mycoplasma pneumoniae-associated lung abscesses in children.
- Prompt treatment facilitates complete lung recovery without sequelae.
- Further research into this rare complication and its optimal management is warranted.
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