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Ofloxacin use in a geriatric population
L E Nicolle1, J Degelau, P Alessi
1University of Manitoba, Winnipeg, Canada.
Chemotherapy
|January 1, 1991
Summary
Ofloxacin shows promise for treating common infections like pneumonia and skin issues in elderly patients. This ongoing trial suggests it is a safe and effective antimicrobial option for this vulnerable population.
Area of Science:
- Infectious Diseases
- Geriatrics
- Pharmacology
Background:
- Institutionalized elderly patients are susceptible to common infections.
- Effective antimicrobial therapy is crucial for this demographic.
- Ofloxacin is being investigated for its potential in treating these infections.
Purpose of the Study:
- To evaluate the efficacy and safety of ofloxacin.
- To assess ofloxacin in treating pneumonia, urinary tract infections, and skin infections.
- To compare ofloxacin with standard therapies in institutionalized elderly individuals.
Main Methods:
- A multicenter North American trial was conducted.
- Two study arms: randomized comparison of IV/oral ofloxacin vs. standard therapy in acute care, and an open study of oral ofloxacin in chronic care.
- 58 subjects enrolled, mean age 84 years.
Main Results:
- Preliminary observations indicate potential safety and efficacy.
- Ofloxacin appears to be a viable treatment option.
- Further data collection is ongoing.
Conclusions:
- Ofloxacin is a potentially safe and effective antimicrobial agent.
- It may be a valuable option for treating common infections in the institutionalized elderly.
- Ongoing study results are encouraging.