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Published on: September 5, 2011
Parameters associated with outcome in third trimester monochorionic diamniotic twin pregnancies
Alon Shrim1, Boaz Weisz2, Liat Gindes2
1Department of Obstetrics and Gynecology, Royal Victoria Hospital, McGill University Health Centre, Montreal QC.
Monochorionic (MC) twin pregnancies face higher risks of perinatal mortality, premature birth, and congenital malformations compared to dichorionic (DC) twins. Close monitoring of MC twins is crucial throughout gestation to manage these risks effectively.
Area of Science:
- Perinatology
- Neonatal Medicine
- Maternal-Fetal Medicine
Background:
- Monochorionic (MC) diamniotic twin pregnancies present unique challenges due to placental sharing.
- These pregnancies are associated with increased risks of perinatal and neonatal complications compared to dichorionic (DC) twins.
Purpose of the Study:
- To evaluate parameters linked to perinatal and neonatal morbidity and mortality in MC diamniotic twin pregnancies.
- To compare outcomes between MC and DC twin pregnancies after 25 weeks of gestation.
Main Methods:
- Retrospective analysis of neonatal outcomes for twin pregnancies (2001-2007) stratified by chorionicity.
- Detailed review of MC pregnancies with intrauterine or neonatal demise to identify contributing factors.
Main Results:
- MC twins exhibited higher perinatal mortality (1.61% vs. 0.35%), lower gestational age at delivery, and reduced birth weights compared to DC twins.
- Severe discordant growth (>20% birth weight difference) was significantly more frequent in MC pregnancies (25.81% vs. 11.68%).
- MC twins showed higher rates of congenital malformations, NICU admissions, and velamentous cord insertions.
Conclusions:
- MC twin pregnancies require frequent monitoring throughout gestation, particularly in the third trimester, even with seemingly normal progression.
- Identifying and managing risks associated with MC twins, such as discordant growth and malformations, is critical for improving outcomes.
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