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Updated: Jun 12, 2026

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
07:38

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Published on: September 25, 2017

UGT2B10 genotype influences nicotine glucuronidation, oxidation, and consumption

Jeannette Zinggeler Berg1, Linda B von Weymarn, Elizabeth A Thompson

  • 1Department of Biochemistry, Molecular Biology, and Biophysics, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
|May 27, 2010
PubMed
Summary

Smokers with a UGT2B10 gene variant (Asp67Tyr) metabolize nicotine differently, leading to reduced nicotine consumption. This genetic factor impacts smoking behavior and should be considered in tobacco research.

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