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Streptococcus pyogenes vulvovaginitis in children in Nottingham
F E Donald1, R C Slack, G Colman
1Department of Microbiology, University Hospital, Queen's Medical Centre, Nottingham.
Epidemiology and Infection
|June 1, 1991
Summary
This study observed a significant increase in Streptococcus pyogenes vaginal isolates in children with vulvovaginitis in Nottingham between 1986-1989. Throat swab infections also rose, with a winter peak noted for both.
Area of Science:
- Microbiology
- Pediatric Infectious Diseases
- Public Health
Background:
- Vulvovaginitis in children can be caused by various pathogens.
- Streptococcus pyogenes (Group A Streptococcus) is a common bacterial pathogen.
- Surveillance of pediatric infections is crucial for public health.
Purpose of the Study:
- To investigate the incidence and characteristics of Streptococcus pyogenes isolates from pediatric vaginal swabs.
- To analyze trends in S. pyogenes infections in children presenting with vulvovaginitis.
- To determine the serotypes and antibiotic sensitivity of vaginal S. pyogenes isolates.
Main Methods:
- Retrospective analysis of S. pyogenes isolates from pediatric vaginal and throat swabs.
- Serotyping of vaginal S. pyogenes strains.
- Erythromycin sensitivity testing (MIC determination).
Main Results:
- 159 S. pyogenes vaginal isolates were identified from 1986-1989, showing a marked increase.
- Vaginal S. pyogenes accounted for 11% of all pediatric vaginal swabs.
- Throat swab isolates also increased, with a winter peak observed for both sample types.
- 22 serotypes were identified, with M4, M6, R28, and M12 being most common (61%).
- 84% of tested strains exhibited high sensitivity to erythromycin.
Conclusions:
- A notable rise in S. pyogenes vaginal infections among children with vulvovaginitis occurred in Nottingham.
- The increasing trend and specific serotypes observed warrant further investigation.
- The findings highlight the importance of monitoring S. pyogenes in pediatric populations.