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Updated: Jun 12, 2026

Murine Model of Central Venous Stenosis using Aortocaval Fistula with an Outflow Stenosis
Published on: July 11, 2019
From excessive high-flow, high-gradient to paradoxical low-flow, low-gradient aortic valve stenosis: hemodialysis
Pierre Vladimir Ennezat1, Sylvestre Maréchaux, Philippe Pibarot
1Division of Cardiology and Ultrasound, Centre Hospitalier Régional et Universitaire de Lille, and EA 2693, Faculté de Médecine, Université de Lille 2, Lille, France. ennezat@yahoo.com
Abstract:
The coexistence of aortic valve stenosis (AS) with hemodialysis arteriovenous (AV) fistula complicates the assessment of the severity of valvular disease. We describe the physiological changes in stenotic indices which occur following manual compression of the AV fistula. The manual compression of the AV fistula is capable of inducing significant alterations in transvalvular flow rates and valvulo-arterial impedance that translates into important changes in aortic valve hemodynamics and grading of stenosis severity.
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