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Sweat-related dermatoses: old concept and new scenario
1Department of Dermatology, Stanford University School of Medicine, Calif.
Dermatologica
|January 1, 1991
Summary
This review highlights skin conditions caused by sweat, proposing a new classification of internal and external sweating. It suggests sweat
Area of Science:
- Dermatology
- Sweat Physiology
- Cutaneous Inflammation
Background:
- Sweat-related dermatoses are underemphasized.
- Existing classifications do not adequately address sweat's role in skin disease.
- New clinical scenarios necessitate a re-evaluation of sweat's impact on skin.
Purpose of the Study:
- To review dermatoses caused by sweat.
- To propose a working classification of sweat-related skin conditions.
- To introduce the concept of sweat-gland-mediated cutaneous inflammation.
Main Methods:
- Literature review of sweat-related dermatoses.
- Clinical observation analysis.
- Development of a novel classification system based on sweat extravasation and location.
Main Results:
- A proposed classification distinguishes between internal (extravasated) and external (surface) sweating.
- Transient acantholytic dermatosis is linked to extravasated sweat and protease-induced acantholysis.
- Neutrophilic eccrine hidradenitis may be a sweat-related drug reaction.
Conclusions:
- Sweat retention syndrome is relevant in hospitalized febrile patients, chemotherapy use, and lifestyle changes.
- A new framework for understanding sweat-gland-mediated cutaneous inflammation is presented.
- Further research into sweat's role in dermatological conditions is warranted.