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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

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Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
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Published on: September 9, 2015

[Mycobacteria at extrapulmonary sites].

J Svobodová1, H Dujsíková, H Jedlicková

  • 1Pracoviste mikrobiologické diagnostiky TBC a mykobakterióz, Zdravotní ústav se sídlem v Brne. jana.svobodova@zu.cz

Klinicka Mikrobiologie a Infekcni Lekarstvi
|May 27, 2010
PubMed
Summary

This report details two mycobacterial infections: rare hepatic tuberculosis and skin infection from Mycobacterium chelonae. It highlights atypical mycobacteria as potential causes of severe disease in immunocompromised individuals.

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Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
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Published on: September 9, 2015

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
08:34

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Published on: September 27, 2018

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Immunology

Background:

  • Mycobacterial infections encompass tuberculosis and diseases caused by non-tuberculous mycobacteria (NTM).
  • Hepatic tuberculosis is a rare manifestation of Mycobacterium tuberculosis infection.
  • Cutaneous mycobacteriosis can be caused by various mycobacterial species, including rapidly growing mycobacteria like Mycobacterium chelonae.

Observation:

  • Presents two distinct cases of mycobacterial infections.
  • Case 1: A rare instance of hepatic tuberculosis.
  • Case 2: Cutaneous mycobacteriosis attributed to Mycobacterium chelonae.

Findings:

  • Mycobacterium tuberculosis can present with unusual organ involvement, such as the liver.
  • Mycobacterium chelonae is an atypical mycobacterium capable of causing significant cutaneous disease.
  • Nontuberculous mycobacteria, including M. chelonae, pose a threat to immunocompromised patients, leading to diverse and severe infections.

Implications:

  • Highlights the diagnostic challenge of rare mycobacterial presentations.
  • Underscores the importance of considering NTM in the differential diagnosis of infections, especially in immunocompromised hosts.
  • Emphasizes the need for awareness regarding the pathogenic potential of atypical mycobacteria in clinical practice.